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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cathepsin L' and Monomerid = 50128962   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin L1


(Homo sapiens (Human))
BDBM50128962
PNG
(CHEMBL294260 | N-{(S)-1-[2-(4-Cyclopentylmethoxy-p...)
Show SMILES COc1ccc(cc1)C(=O)N[C@@H](CC(C)C)C(=O)NCCNc1ccc(OCC2CCCC2)cc1
Show InChI InChI=1S/C28H39N3O4/c1-20(2)18-26(31-27(32)22-8-12-24(34-3)13-9-22)28(33)30-17-16-29-23-10-14-25(15-11-23)35-19-21-6-4-5-7-21/h8-15,20-21,26,29H,4-7,16-19H2,1-3H3,(H,30,33)(H,31,32)/t26-/m0/s1
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Similars

Article
PubMed
n/an/a 580n/an/an/an/an/an/a



Novartis Pharma AG

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant human cathepsin L activity


Bioorg Med Chem Lett 13: 1997-2001 (2003)


Article DOI: 10.1016/s0960-894x(03)00344-5
BindingDB Entry DOI: 10.7270/Q2VD6XTQ
More data for this
Ligand-Target Pair