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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Monomerid = 50129394   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50129394
PNG
((R)-2-((R)-3,3-Difluoro-cyclopentyl)-1-[4-(2-dimet...)
Show SMILES CN(C)CCC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1
Show InChI InChI=1S/C22H32F2N2O2/c1-25(2)13-9-17-10-14-26(15-11-17)20(27)22(28,18-6-4-3-5-7-18)19-8-12-21(23,24)16-19/h3-7,17,19,28H,8-16H2,1-2H3/t19-,22+/m1/s1
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PC sid
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Similars

Article
PubMed
930n/an/an/an/an/an/an/an/a



Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells


Bioorg Med Chem Lett 13: 2167-72 (2003)


Article DOI: 10.1016/s0960-894x(03)00350-0
BindingDB Entry DOI: 10.7270/Q29G5M68
More data for this
Ligand-Target Pair