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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Monomerid = 50130713   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neprilysin


(Homo sapiens (Human))
BDBM50130713
PNG
(CHEMBL326801 | Thioacetic acid S-(2-benzylcarbamoy...)
Show SMILES CC(CSC(C)=O)C(=O)NCc1ccccc1
Show InChI InChI=1S/C13H17NO2S/c1-10(9-17-11(2)15)13(16)14-8-12-6-4-3-5-7-12/h3-7,10H,8-9H2,1-2H3,(H,14,16)
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CHEMBL
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Institute of Biomedical Chemistry of Russian Academy of Medical Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against neutral endopeptidase (NEP) from human blood serum


J Med Chem 46: 3326-32 (2003)


Article DOI: 10.1021/jm021089h
BindingDB Entry DOI: 10.7270/Q2K07512
More data for this
Ligand-Target Pair