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Found 1 hit Enz. Inhib. hit(s) with Target = 'Poliovirus type 1 polyprotein' and Monomerid = 50137464   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Poliovirus type 1 polyprotein


(Poliovirus type 1 (strain Mahoney))
BDBM50137464
PNG
(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES COc1ccc(CCNC(=O)c2ccc3n(C4CCCCC4)c(nc3c2)-c2ccccn2)cc1OC
Show InChI InChI=1S/C29H32N4O3/c1-35-26-14-11-20(18-27(26)36-2)15-17-31-29(34)21-12-13-25-24(19-21)32-28(23-10-6-7-16-30-23)33(25)22-8-4-3-5-9-22/h6-7,10-14,16,18-19,22H,3-5,8-9,15,17H2,1-2H3,(H,31,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against polio virus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.023
BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair