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Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, brain' and Monomerid = 50141076   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50141076
PNG
(6-[4-(2-Pyrrolidin-1-yl-ethoxy)-naphthalen-1-yl]-p...)
Show SMILES Nc1cccc(n1)-c1ccc(OCCN2CCCC2)c2ccccc12
Show InChI InChI=1S/C21H23N3O/c22-21-9-5-8-19(23-21)17-10-11-20(18-7-2-1-6-16(17)18)25-15-14-24-12-3-4-13-24/h1-2,5-11H,3-4,12-15H2,(H2,22,23)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
In vitro inhibition of human neuronal nitric oxide synthase


J Med Chem 47: 1575-86 (2004)


Article DOI: 10.1021/jm030519g
BindingDB Entry DOI: 10.7270/Q2J102MT
More data for this
Ligand-Target Pair