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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, brain' and Monomerid = 50141077   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50141077
PNG
(6-[4-(1-Methyl-pyrrolidin-2-ylmethoxy)-naphthalen-...)
Show SMILES CN1CCCC1COc1ccc(-c2cccc(N)n2)c2ccccc12
Show InChI InChI=1/C21H23N3O/c1-24-13-5-6-15(24)14-25-20-12-11-17(16-7-2-3-8-18(16)20)19-9-4-10-21(22)23-19/h2-4,7-12,15H,5-6,13-14H2,1H3,(H2,22,23)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 112n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
In vitro inhibition of human neuronal nitric oxide synthase


J Med Chem 47: 1575-86 (2004)


Article DOI: 10.1021/jm030519g
BindingDB Entry DOI: 10.7270/Q2J102MT
More data for this
Ligand-Target Pair