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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, endothelial' and Monomerid = 50141087   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50141087
PNG
(6-{4-[2-(4-Dimethylamino-piperidin-1-yl)-ethoxy]-n...)
Show SMILES CN(C)C1CCN(CCOc2ccc(-c3cccc(N)n3)c3ccccc23)CC1
Show InChI InChI=1S/C24H30N4O/c1-27(2)18-12-14-28(15-13-18)16-17-29-23-11-10-20(19-6-3-4-7-21(19)23)22-8-5-9-24(25)26-22/h3-11,18H,12-17H2,1-2H3,(H2,25,26)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 7.03E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
In vitro inhibition of human endothelial nitric oxide synthase


J Med Chem 47: 1575-86 (2004)


Article DOI: 10.1021/jm030519g
BindingDB Entry DOI: 10.7270/Q2J102MT
More data for this
Ligand-Target Pair