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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, endothelial' and Monomerid = 50141088   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50141088
PNG
(6-[4-(2-Dimethylamino-ethoxy)-6,7,8,9-tetrahydro-5...)
Show SMILES CN(C)CCOc1ccc(-c2cccc(N)n2)c2CCCCCc12
Show InChI InChI=1S/C20H27N3O/c1-23(2)13-14-24-19-12-11-16(18-9-6-10-20(21)22-18)15-7-4-3-5-8-17(15)19/h6,9-12H,3-5,7-8,13-14H2,1-2H3,(H2,21,22)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.75E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
In vitro inhibition of human endothelial nitric oxide synthase


J Med Chem 47: 1575-86 (2004)


Article DOI: 10.1021/jm030519g
BindingDB Entry DOI: 10.7270/Q2J102MT
More data for this
Ligand-Target Pair