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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Plasmin' and Monomerid = 50142157   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Plasminogen


(Homo sapiens (Human))
BDBM50142157
PNG
(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-imino-t...)
Show SMILES NC1=NCCCN1Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1
Show InChI InChI=1S/C24H22Cl2N6O2/c25-17-6-8-20(19(12-17)23(34)31-21-9-7-18(26)13-29-21)30-22(33)16-4-2-15(3-5-16)14-32-11-1-10-28-24(32)27/h2-9,12-13H,1,10-11,14H2,(H2,27,28)(H,30,33)(H,29,31,34)
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Article
PubMed
n/an/a>1.10E+4n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against plasmin.


Bioorg Med Chem Lett 14: 989-93 (2004)


Article DOI: 10.1016/j.bmcl.2003.11.080
BindingDB Entry DOI: 10.7270/Q2X34WXD
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM50142157
PNG
(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(2-imino-t...)
Show SMILES NC1=NCCCN1Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1
Show InChI InChI=1S/C24H22Cl2N6O2/c25-17-6-8-20(19(12-17)23(34)31-21-9-7-18(26)13-29-21)30-22(33)16-4-2-15(3-5-16)14-32-11-1-10-28-24(32)27/h2-9,12-13H,1,10-11,14H2,(H2,27,28)(H,30,33)(H,29,31,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.10E+4n/an/an/an/an/an/a



Millennium Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against tissue type plasminogen activator.


Bioorg Med Chem Lett 14: 989-93 (2004)


Article DOI: 10.1016/j.bmcl.2003.11.080
BindingDB Entry DOI: 10.7270/Q2X34WXD
More data for this
Ligand-Target Pair