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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Urokinase-type plasminogen activator' and Monomerid = 50147428   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50147428
PNG
(CHEMBL110358 | N-(5-Bromo-isoquinolin-1-yl)-guanid...)
Show SMILES NC(N)=Nc1nccc2c(Br)cccc12
Show InChI InChI=1S/C10H9BrN4/c11-8-3-1-2-7-6(8)4-5-14-9(7)15-10(12)13/h1-5H,(H4,12,13,14,15)
PDB
MMDB

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Similars

Article
PubMed
4.93E+3n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against human urokinase-type plasminogen activator was evaluated using S-2444 as substrate


Bioorg Med Chem Lett 14: 3227-30 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.094
BindingDB Entry DOI: 10.7270/Q2125S3C
More data for this
Ligand-Target Pair