BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50150620   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50150620
PNG
(6-(4-Methyl-piperazin-1-yl)-6-oxo-hexanoic acid {4...)
Show SMILES CN1CCN(CC1)C(=O)CCCCC(=O)Nc1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1
Show InChI InChI=1S/C44H57N9O4/c1-50-26-28-53(29-27-50)43(57)9-3-2-8-40(54)45-32-10-12-33(13-11-32)48-44-36-16-14-34(46-41(55)18-24-51-20-4-5-21-51)30-38(36)49-39-31-35(15-17-37(39)44)47-42(56)19-25-52-22-6-7-23-52/h10-17,30-31H,2-9,18-29H2,1H3,(H,45,54)(H,46,55)(H,47,56)(H,48,49)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 165n/an/an/an/a



University of London School of Pharmacy

Curated by ChEMBL


Assay Description
Effective concentration against telomerase by TRAP


Bioorg Med Chem Lett 14: 4347-51 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.090
BindingDB Entry DOI: 10.7270/Q2KD1XDZ
More data for this
Ligand-Target Pair