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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, endothelial' and Monomerid = 50150886   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, endothelial


(Homo sapiens (Human))
BDBM50150886
PNG
(6-[4-(2-Dimethylamino-ethyl)-2,5-dimethoxy-phenyl]...)
Show SMILES COc1cc(c(OC)cc1CCN(C)C)-c1cccc(N)n1
Show InChI InChI=1S/C17H23N3O2/c1-20(2)9-8-12-10-16(22-4)13(11-15(12)21-3)14-6-5-7-17(18)19-14/h5-7,10-11H,8-9H2,1-4H3,(H2,18,19)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>3.20E+4n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against endothelial nitric oxide synthase in human


Bioorg Med Chem Lett 14: 4511-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.043
BindingDB Entry DOI: 10.7270/Q28S4QP6
More data for this
Ligand-Target Pair