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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 4D' and Monomerid = 50151547   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))
BDBM50151547
PNG
(5-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Show SMILES Cn1nc(s\c1=N/c1ccc(F)c(c1)C(O)=O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C16H11ClFN3O2S/c1-21-16(19-11-6-7-13(18)12(8-11)15(22)23)24-14(20-21)9-2-4-10(17)5-3-9/h2-8H,1H3,(H,22,23)/b19-16-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.97E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 4D3 expressed in baculovirus infected Sf9 cells


Bioorg Med Chem Lett 14: 4607-13 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.008
BindingDB Entry DOI: 10.7270/Q2377855
More data for this
Ligand-Target Pair