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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Monomerid = 50153745   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50153745
PNG
(CHEMBL183756 | N-{4-[4-(4-Acetyl-3-hydroxy-2-propy...)
Show SMILES CCCc1c(O)c(ccc1OCCCCOc1ccc(cc1)C(=O)NS(C)(=O)=O)C(C)=O
Show InChI InChI=1S/C23H29NO7S/c1-4-7-20-21(13-12-19(16(2)25)22(20)26)31-15-6-5-14-30-18-10-8-17(9-11-18)23(27)24-32(3,28)29/h8-13,26H,4-7,14-15H2,1-3H3,(H,24,27)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.04E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assay


Bioorg Med Chem Lett 14: 5329-32 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.020
BindingDB Entry DOI: 10.7270/Q21Z43W0
More data for this
Ligand-Target Pair