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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Monomerid = 50153746   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50153746
PNG
(1-(2-Hydroxy-3-propyl-4-{4-[4-(2H-tetrazol-5-yl)-p...)
Show SMILES CCCc1c(OCCCCNc2ccc(cc2)-c2nnn[nH]2)ccc(C(C)=O)c1O
Show InChI InChI=1S/C22H27N5O3/c1-3-6-19-20(12-11-18(15(2)28)21(19)29)30-14-5-4-13-23-17-9-7-16(8-10-17)22-24-26-27-25-22/h7-12,23,29H,3-6,13-14H2,1-2H3,(H,24,25,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 939n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assay


Bioorg Med Chem Lett 14: 5329-32 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.020
BindingDB Entry DOI: 10.7270/Q21Z43W0
More data for this
Ligand-Target Pair