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Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50154994   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50154994
PNG
(2-[2-(5-Fluoro-3''-methyl-biphenyl-3-yl)-2H-tetraz...)
Show SMILES Cc1cccc(c1)-c1cc(F)cc(c1)-n1nnc(n1)-c1ccccn1
Show InChI InChI=1S/C19H14FN5/c1-13-5-4-6-14(9-13)15-10-16(20)12-17(11-15)25-23-19(22-24-25)18-7-2-3-8-21-18/h2-12H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonistic activity against Metabotropic glutamate receptor 5 in [Ca2+] flux assay


Bioorg Med Chem Lett 14: 5485-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.016
BindingDB Entry DOI: 10.7270/Q21V5DGP
More data for this
Ligand-Target Pair