BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50154995   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50154995
PNG
(2-[2-(3-fluoro-5-pyridin-4-ylphenyl)-2H-tetrazol-5...)
Show SMILES Fc1cc(cc(c1)-n1nnc(n1)-c1ccccn1)-c1ccncc1
Show InChI InChI=1S/C17H11FN6/c18-14-9-13(12-4-7-19-8-5-12)10-15(11-14)24-22-17(21-23-24)16-3-1-2-6-20-16/h1-11H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 806n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonistic activity against Metabotropic glutamate receptor 5 in [Ca2+] flux assay


Bioorg Med Chem Lett 14: 5485-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.016
BindingDB Entry DOI: 10.7270/Q21V5DGP
More data for this
Ligand-Target Pair