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Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50155012   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50155012
PNG
(2-[2-(3-pyridin-3-ylphenyl)-2H-tetrazol-5-yl]pyrid...)
Show SMILES c1ccc(nc1)-c1nnn(n1)-c1cccc(c1)-c1cccnc1
Show InChI InChI=1S/C17H12N6/c1-2-10-19-16(8-1)17-20-22-23(21-17)15-7-3-5-13(11-15)14-6-4-9-18-12-14/h1-12H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 63n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonistic activity against Metabotropic glutamate receptor 5 in [Ca2+] flux assay


Bioorg Med Chem Lett 14: 5485-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.016
BindingDB Entry DOI: 10.7270/Q21V5DGP
More data for this
Ligand-Target Pair