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Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50155657   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50155657
PNG
(3-(4-Methyl-piperazin-1-yl)-N-{7-[3-(4-methyl-pipe...)
Show SMILES CN1CCN(CCC(=O)Nc2ccc3nc4ccc(NC(=O)CCN5CCN(C)CC5)cc4c(O)c3c2)CC1
Show InChI InChI=1S/C29H39N7O3/c1-33-11-15-35(16-12-33)9-7-27(37)30-21-3-5-25-23(19-21)29(39)24-20-22(4-6-26(24)32-25)31-28(38)8-10-36-17-13-34(2)14-18-36/h3-6,19-20H,7-18H2,1-2H3,(H,30,37)(H,31,38)(H,32,39)
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Article
PubMed
n/an/an/an/a 1.90E+3n/an/an/an/a



University of London

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% of telomerase activity


Bioorg Med Chem Lett 14: 5845-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.037
BindingDB Entry DOI: 10.7270/Q26D5SG9
More data for this
Ligand-Target Pair