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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50155665   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50155665
PNG
(3-(4-Ethyl-piperazin-1-yl)-N-{6-[3-(4-ethyl-pipera...)
Show SMILES CCN1CCN(CCC(=O)Nc2ccc3c(O)c4ccc(NC(=O)CCN5CCN(CC)CC5)cc4nc3c2)CC1
Show InChI InChI=1S/C31H43N7O3/c1-3-35-13-17-37(18-14-35)11-9-29(39)32-23-5-7-25-27(21-23)34-28-22-24(6-8-26(28)31(25)41)33-30(40)10-12-38-19-15-36(4-2)16-20-38/h5-8,21-22H,3-4,9-20H2,1-2H3,(H,32,39)(H,33,40)(H,34,41)
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Article
PubMed
n/an/an/an/a 1.90E+3n/an/an/an/a



University of London

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% of telomerase activity


Bioorg Med Chem Lett 14: 5845-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.037
BindingDB Entry DOI: 10.7270/Q26D5SG9
More data for this
Ligand-Target Pair