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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cathepsin L' and Monomerid = 50156091   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin L1


(Homo sapiens (Human))
BDBM50156091
PNG
((2S,3S,4R,5R)-5-(6-Cyclohexylamino-2-hydroxymethyl...)
Show SMILES OCc1nc(NC2CCCCC2)c2ncn([C@@H]3O[C@H](O)[C@@H](O)[C@H]3O)c2n1
Show InChI InChI=1S/C16H23N5O5/c22-6-9-19-13(18-8-4-2-1-3-5-8)10-14(20-9)21(7-17-10)15-11(23)12(24)16(25)26-15/h7-8,11-12,15-16,22-25H,1-6H2,(H,18,19,20)/t11-,12+,15-,16+/m1/s1
PDB
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PC cid
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Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibitory concentration against recombinant human cathepsin L by using Z-Phe-Arg-AMC as synthetic substrate


J Med Chem 47: 5833-6 (2004)


Article DOI: 10.1021/jm0493111
BindingDB Entry DOI: 10.7270/Q2862FWZ
More data for this
Ligand-Target Pair