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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50156588   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50156588
PNG
(1-(4-trifluoromethoxyphenyl)-3-[3-fluoro-5-(4-meth...)
Show SMILES COC1(CCOCC1)c1cc(F)cc(OCc2cc(-c3ccccc3)n(n2)-c2ccc(OC(F)(F)F)cc2)c1
Show InChI InChI=1S/C29H26F4N2O4/c1-36-28(11-13-37-14-12-28)21-15-22(30)17-26(16-21)38-19-23-18-27(20-5-3-2-4-6-20)35(34-23)24-7-9-25(10-8-24)39-29(31,32)33/h2-10,15-18H,11-14,19H2,1H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 850n/an/an/an/an/an/a



Université de Lille 2

Curated by ChEMBL


Assay Description
Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysis


J Med Chem 47: 6195-206 (2004)


Article DOI: 10.1021/jm0407761
BindingDB Entry DOI: 10.7270/Q2DR2V01
More data for this
Ligand-Target Pair