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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50156592   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50156592
PNG
(1-(4-methanesulfonylphenyl)-3-[(3,5-dimethoxy)phen...)
Show SMILES COc1cc(OC)cc(OCc2cc(-c3ccccc3)n(n2)-c2ccc(cc2)S(C)(=O)=O)c1
Show InChI InChI=1S/C25H24N2O5S/c1-30-21-14-22(31-2)16-23(15-21)32-17-19-13-25(18-7-5-4-6-8-18)27(26-19)20-9-11-24(12-10-20)33(3,28)29/h4-16H,17H2,1-3H3
PDB
MMDB

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Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Université de Lille 2

Curated by ChEMBL


Assay Description
Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysis


J Med Chem 47: 6195-206 (2004)


Article DOI: 10.1021/jm0407761
BindingDB Entry DOI: 10.7270/Q2DR2V01
More data for this
Ligand-Target Pair