BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50161019   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50161019
PNG
(3-Hydroxy-6-methyl-pyridine-2-carboxylic acid (6-m...)
Show SMILES Cc1cccc(NC(=O)c2nc(C)ccc2O)n1
Show InChI InChI=1S/C13H13N3O2/c1-8-4-3-5-11(14-8)16-13(18)12-10(17)7-6-9(2)15-12/h3-7,17H,1-2H3,(H,14,16,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection


Bioorg Med Chem Lett 15: 4350-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.059
BindingDB Entry DOI: 10.7270/Q2QZ29H0
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50161019
PNG
(3-Hydroxy-6-methyl-pyridine-2-carboxylic acid (6-m...)
Show SMILES Cc1cccc(NC(=O)c2nc(C)ccc2O)n1
Show InChI InChI=1S/C13H13N3O2/c1-8-4-3-5-11(14-8)16-13(18)12-10(17)7-6-9(2)15-12/h3-7,17H,1-2H3,(H,14,16,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration against human recombinant metabotropic glutamate receptor 5 (mGlu5) in Ltk cells determined using fluorescence detection met...


Bioorg Med Chem Lett 15: 1197-200 (2005)


Article DOI: 10.1016/j.bmcl.2004.11.078
BindingDB Entry DOI: 10.7270/Q28G8K6P
More data for this
Ligand-Target Pair