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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Monomerid = 50163608   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50163608
PNG
((3-Ethyl-2-methoxy-quinolin-6-yl)-(4-methoxy-cyclo...)
Show SMILES Cc1cc2cc(ccc2[nH]c1=O)C(C)(C#N)c1ccccc1
Show InChI InChI=1/C19H16N2O/c1-13-10-14-11-16(8-9-17(14)21-18(13)22)19(2,12-20)15-6-4-3-5-7-15/h3-11H,1-2H3,(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against human metabotropic glutamate receptor 1 transmembrane domain


J Med Chem 48: 2134-53 (2005)


Article DOI: 10.1021/jm049499o
BindingDB Entry DOI: 10.7270/Q2RR2017
More data for this
Ligand-Target Pair