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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Monomerid = 50163618   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50163618
PNG
((3-Ethyl-2-thiophen-3-yl-quinolin-6-yl)-(4-methoxy...)
Show SMILES CCc1cc2cc(ccc2nc1-c1ccsc1)C(=O)C1CCC(CC1)OC
Show InChI InChI=1S/C23H25NO2S/c1-3-15-12-19-13-17(23(25)16-4-7-20(26-2)8-5-16)6-9-21(19)24-22(15)18-10-11-27-14-18/h6,9-14,16,20H,3-5,7-8H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 191n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against human metabotropic glutamate receptor


J Med Chem 48: 2134-53 (2005)


Article DOI: 10.1021/jm049499o
BindingDB Entry DOI: 10.7270/Q2RR2017
More data for this
Ligand-Target Pair