BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, inducible' and Monomerid = 50165431   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, inducible


(Homo sapiens (Human))
BDBM50165431
PNG
((4aS,6aS,6bR,12aR)-11-Cyano-2,2,6a,6b,9,9,12a-hept...)
Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C=C(C#N)C(=O)C(C)(C)C5CC[C@@]34C)C2C1)C(O)=O
Show InChI InChI=1S/C31H43NO3/c1-26(2)12-14-31(25(34)35)15-13-29(6)20(21(31)17-26)8-9-23-28(5)16-19(18-32)24(33)27(3,4)22(28)10-11-30(23,29)7/h8,16,21-23H,9-15,17H2,1-7H3,(H,34,35)/t21?,22?,23?,28-,29+,30+,31-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 600n/an/an/an/an/an/a



Dartmouth College

Curated by ChEMBL


Assay Description
Inhibition of inducible nitric oxide synthase in activated macrophages


Bioorg Med Chem Lett 15: 2215-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.031
BindingDB Entry DOI: 10.7270/Q23N245R
More data for this
Ligand-Target Pair