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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Monomerid = 50170309   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50170309
PNG
(1-(2,2-Dimethyl-propyl)-4-propyl-5-[3-(1H-tetrazol...)
Show SMILES CCCc1c(Oc2cccc(c2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12
Show InChI InChI=1S/C23H27N5O/c1-5-7-19-18-12-13-28(15-23(2,3)4)20(18)10-11-21(19)29-17-9-6-8-16(14-17)22-24-26-27-25-22/h6,8-14H,5,7,15H2,1-4H3,(H,24,25,26,27)
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Similars

Article
PubMed
n/an/an/an/a 134n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr


Bioorg Med Chem Lett 15: 4068-72 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.017
BindingDB Entry DOI: 10.7270/Q2Q52P6K
More data for this
Ligand-Target Pair