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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50171059   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50171059
PNG
((3-Ethoxy-5-p-tolyl-pyridin-2-yl)-(6-methyl-pyridi...)
Show SMILES CCOc1cc(cnc1Nc1cccc(C)n1)-c1ccc(C)cc1
Show InChI InChI=1S/C20H21N3O/c1-4-24-18-12-17(16-10-8-14(2)9-11-16)13-21-20(18)23-19-7-5-6-15(3)22-19/h5-13H,4H2,1-3H3,(H,21,22,23)
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Similars

Article
PubMed
n/an/a 513n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection


Bioorg Med Chem Lett 15: 4350-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.059
BindingDB Entry DOI: 10.7270/Q2QZ29H0
More data for this
Ligand-Target Pair