BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-1' and Monomerid = 50173231   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-14 (MMP14)


(Homo sapiens (Human))
BDBM50173231
PNG
((S)-2-{4'-[(5-Chloro-4-isopropoxy-3-methyl-benzofu...)
Show SMILES CC(C)Oc1c(Cl)ccc2oc(C(=O)Nc3ccc(cc3)-c3ccc(cc3)S(=O)(=O)N[C@@H](C(C)C)C(O)=O)c(C)c12
Show InChI InChI=1S/C30H31ClN2O7S/c1-16(2)26(30(35)36)33-41(37,38)22-12-8-20(9-13-22)19-6-10-21(11-7-19)32-29(34)27-18(5)25-24(40-27)15-14-23(31)28(25)39-17(3)4/h6-17,26,33H,1-5H3,(H,32,34)(H,35,36)/t26-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.00E+4n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibitory concentration against MMP-14


Bioorg Med Chem Lett 15: 4961-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.001
BindingDB Entry DOI: 10.7270/Q20Z72TH
More data for this
Ligand-Target Pair
Matrix metalloproteinase-14 (MMP14)


(Homo sapiens (Human))
BDBM50173231
PNG
((S)-2-{4'-[(5-Chloro-4-isopropoxy-3-methyl-benzofu...)
Show SMILES CC(C)Oc1c(Cl)ccc2oc(C(=O)Nc3ccc(cc3)-c3ccc(cc3)S(=O)(=O)N[C@@H](C(C)C)C(O)=O)c(C)c12
Show InChI InChI=1S/C30H31ClN2O7S/c1-16(2)26(30(35)36)33-41(37,38)22-12-8-20(9-13-22)19-6-10-21(11-7-19)32-29(34)27-18(5)25-24(40-27)15-14-23(31)28(25)39-17(3)4/h6-17,26,33H,1-5H3,(H,32,34)(H,35,36)/t26-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.01E+4n/an/an/an/an/an/a



Pomona College

Curated by ChEMBL


Assay Description
Inhibition of MMP14


Bioorg Med Chem 15: 2223-68 (2007)


Article DOI: 10.1016/j.bmc.2007.01.011
BindingDB Entry DOI: 10.7270/Q2571DBD
More data for this
Ligand-Target Pair