BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50175904   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50175904
PNG
(8-[(1S,2S)-2-(4-chloro-phenyl)-cyclohexyl]-1-pheny...)
Show SMILES Clc1ccc(cc1)[C@@H]1CCCC[C@@H]1N1CCC2(CC1)N(CNC2=O)c1ccccc1
Show InChI InChI=1S/C25H30ClN3O/c26-20-12-10-19(11-13-20)22-8-4-5-9-23(22)28-16-14-25(15-17-28)24(30)27-18-29(25)21-6-2-1-3-7-21/h1-3,6-7,10-13,22-23H,4-5,8-9,14-18H2,(H,27,30)/t22-,23-/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 40n/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake in cells transfected with human GlyT1 cDNA


Bioorg Med Chem Lett 16: 349-53 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.075
BindingDB Entry DOI: 10.7270/Q2XK8F42
More data for this
Ligand-Target Pair