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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50175911   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50175911
PNG
(1-hexyl-8-((1S,2S)-2-phenyl-cyclohexyl)-1,3,8-tria...)
Show SMILES CCCCCCN1CNC(=O)C11CCN(CC1)[C@H]1CCCC[C@H]1c1ccccc1
Show InChI InChI=1S/C25H39N3O/c1-2-3-4-10-17-28-20-26-24(29)25(28)15-18-27(19-16-25)23-14-9-8-13-22(23)21-11-6-5-7-12-21/h5-7,11-12,22-23H,2-4,8-10,13-20H2,1H3,(H,26,29)/t22-,23-/m0/s1
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Similars

Article
PubMed
n/an/an/an/a 49n/an/an/an/a



F. Hoffmann-La Roche Inc

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake in cells transfected with human GlyT1 cDNA


Bioorg Med Chem Lett 16: 349-53 (2005)


Article DOI: 10.1016/j.bmcl.2005.09.075
BindingDB Entry DOI: 10.7270/Q2XK8F42
More data for this
Ligand-Target Pair