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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 4C' and Monomerid = 50176521   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Homo sapiens (Human))
BDBM50176521
PNG
(5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...)
Show SMILES CN1C(=O)C(C(=O)Nc2nncs2)c2cc3occc3cc12
Show InChI InChI=1/C14H10N4O3S/c1-18-9-4-7-2-3-21-10(7)5-8(9)11(13(18)20)12(19)16-14-17-15-6-22-14/h2-6,11H,1H3,(H,16,17,19)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.60E+4n/an/an/an/an/an/a



Pfizer, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against PDE4C by scintillation proximity assay


Bioorg Med Chem Lett 16: 307-10 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.005
BindingDB Entry DOI: 10.7270/Q2XD118H
More data for this
Ligand-Target Pair