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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50178425   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50178425
PNG
(2-((3-(1,3-dioxo-2-phenyl-2,3-dihydro-1H-inden-2-y...)
Show SMILES CN(CCCC1(C(=O)c2ccccc2C1=O)c1ccccc1)CC(O)=O
Show InChI InChI=1S/C21H21NO4/c1-22(14-18(23)24)13-7-12-21(15-8-3-2-4-9-15)19(25)16-10-5-6-11-17(16)20(21)26/h2-6,8-11H,7,12-14H2,1H3,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of uptake of [14C]glycine into human JAR cells expressing human GlyT1


Bioorg Med Chem Lett 16: 1388-91 (2006)


Article DOI: 10.1016/j.bmcl.2005.11.041
BindingDB Entry DOI: 10.7270/Q29C6X13
More data for this
Ligand-Target Pair