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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50179649   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50179649
PNG
(1-hexyl-3-(1-methyl-4-oxoimidazolidin-2-ylidene)ur...)
Show SMILES CCCCCCNC(=O)Nc1nc(O)cn1C
Show InChI InChI=1S/C11H20N4O2/c1-3-4-5-6-7-12-11(17)14-10-13-9(16)8-15(10)2/h8,16H,3-7H2,1-2H3,(H2,12,13,14,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



AstraZeneca R&D

Curated by ChEMBL


Assay Description
Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPR


Bioorg Med Chem Lett 16: 1142-5 (2006)


Article DOI: 10.1016/j.bmcl.2005.11.092
BindingDB Entry DOI: 10.7270/Q2697348
More data for this
Ligand-Target Pair