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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclooxygenase-1' and Monomerid = 50181914   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclooxygenase-1 (COX-1)


(Homo sapiens (Human))
BDBM50181914
PNG
(2-(2-Fluoro-biphenyl-4-yl)-2-methyl-propionic acid...)
Show SMILES CC(C)(C(O)=O)c1ccc(c(F)c1)-c1ccccc1
Show InChI InChI=1S/C16H15FO2/c1-16(2,15(18)19)12-8-9-13(14(17)10-12)11-6-4-3-5-7-11/h3-10H,1-2H3,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of COX1 in human whole blood


Bioorg Med Chem Lett 16: 2219-23 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.033
BindingDB Entry DOI: 10.7270/Q2M32VC8
More data for this
Ligand-Target Pair