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Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50182805   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50182805
PNG
((4-chlorophenyl)(2-(pyridin-2-yl)pyrimidin-4-yl)me...)
Show SMILES OC(c1ccc(Cl)cc1)c1ccnc(n1)-c1ccccn1
Show InChI InChI=1S/C16H12ClN3O/c17-12-6-4-11(5-7-12)15(21)13-8-10-19-16(20-13)14-3-1-2-9-18-14/h1-10,15,21H
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a>3.00E+3n/an/an/an/an/an/a



NPS Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPR


Bioorg Med Chem Lett 16: 2467-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.100
BindingDB Entry DOI: 10.7270/Q22Z1544
More data for this
Ligand-Target Pair