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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-Activated Protein Kinase 1' and Monomerid = 50183851   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 1


(Homo sapiens (human))
BDBM50183851
PNG
((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Show SMILES COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN1CCC[C@@H]1C(=O)N(C)C
Show InChI InChI=1S/C23H25ClFN5O2/c1-29(2)23(31)19-8-5-9-30(19)12-14-10-15-18(11-20(14)32-3)26-13-27-22(15)28-17-7-4-6-16(24)21(17)25/h4,6-7,10-11,13,19H,5,8-9,12H2,1-3H3,(H,26,27,28)/t19-/m1/s1
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Centre de Recherches

Curated by ChEMBL


Assay Description
Inhibition of MAPK


Bioorg Med Chem Lett 16: 2672-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.025
BindingDB Entry DOI: 10.7270/Q25H7FVK
More data for this
Ligand-Target Pair