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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50187872   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50187872
PNG
((2S)-1-(2-(2-(3-fluorophenylthio)-4-(thiophen-3-yl...)
Show SMILES OC(=O)[C@@H]1CCCN1CCOc1ccc(cc1Sc1cccc(F)c1)-c1ccsc1
Show InChI InChI=1S/C23H22FNO3S2/c24-18-3-1-4-19(14-18)30-22-13-16(17-8-12-29-15-17)6-7-21(22)28-11-10-25-9-2-5-20(25)23(26)27/h1,3-4,6-8,12-15,20H,2,5,9-11H2,(H,26,27)/t20-/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 520n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake at human GlyT1b transporter


Bioorg Med Chem Lett 16: 3981-4 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.017
BindingDB Entry DOI: 10.7270/Q2NS0TGN
More data for this
Ligand-Target Pair