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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SRC' and Monomerid = 50188340   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50188340
PNG
(4-(2-chloro-5-hydroxy-phenyl)-8-[4-(4-methyl-piper...)
Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc3C=C(N4N(CCC4=O)c3n2)c2cc(O)ccc2Cl)cc1
Show InChI InChI=1S/C26H26ClN7O2/c1-31-10-12-32(13-11-31)19-4-2-18(3-5-19)29-26-28-16-17-14-23(21-15-20(35)6-7-22(21)27)34-24(36)8-9-33(34)25(17)30-26/h2-7,14-16,35H,8-13H2,1H3,(H,28,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 764n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Src in presence of 10 mM ATP


Bioorg Med Chem Lett 16: 4257-61 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.072
BindingDB Entry DOI: 10.7270/Q22V2FQD
More data for this
Ligand-Target Pair