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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50188379   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50188379
PNG
(4-(4-fluorophenyl)-8-[2-(3-fluorophenyl)-2-hydroxy...)
Show SMILES CC1CC2(CCN1C1CCCCC1(O)c1cccc(F)c1)C(CNC2=O)c1ccc(F)cc1
Show InChI InChI=1/C27H32F2N2O2/c1-18-16-26(23(17-30-25(26)32)19-8-10-21(28)11-9-19)13-14-31(18)24-7-2-3-12-27(24,33)20-5-4-6-22(29)15-20/h4-6,8-11,15,18,23-24,33H,2-3,7,12-14,16-17H2,1H3,(H,30,32)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 474n/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake at human GlyT1 by radiometric assay


Bioorg Med Chem Lett 16: 4311-5 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.058
BindingDB Entry DOI: 10.7270/Q2Z31Z8W
More data for this
Ligand-Target Pair