Compile Data Set for Download or QSAR
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Found 5 Enz. Inhib. hit(s) with Target = 'Thromboxane A2 receptor' and Monomerid = 50188623
TargetThromboxane A2 receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50188623(CHEMBL380274 | N-tert-butyl-N'-[2-(4-methylphenylt...)
Affinity DataIC50:  0.770nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50188623(CHEMBL380274 | N-tert-butyl-N'-[2-(4-methylphenylt...)
Affinity DataIC50:  1.74nMAssay Description:Displacement of [3H]SQ29,548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50188623(CHEMBL380274 | N-tert-butyl-N'-[2-(4-methylphenylt...)
Affinity DataIC50:  55.2nMAssay Description:Activity at TPbeta (long isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50188623(CHEMBL380274 | N-tert-butyl-N'-[2-(4-methylphenylt...)
Affinity DataIC50:  294nMAssay Description:Activity at TPalpha (short isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50188623(CHEMBL380274 | N-tert-butyl-N'-[2-(4-methylphenylt...)
Affinity DataIC50:  800nMAssay Description:Inhibition of U46619-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed