BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50188808   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50188808
PNG
(4-(4-methoxy-phenyl)-8-(2-p-tolyl-cyclohexyl)-2,8-...)
Show SMILES COc1ccc(cc1)C1CNC(=O)C11CCN(CC1)C1CCCCC1c1ccc(C)cc1
Show InChI InChI=1S/C28H36N2O2/c1-20-7-9-21(10-8-20)24-5-3-4-6-26(24)30-17-15-28(16-18-30)25(19-29-27(28)31)22-11-13-23(32-2)14-12-22/h7-14,24-26H,3-6,15-19H2,1-2H3,(H,29,31)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.13E+3n/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake at GlyT1


Bioorg Med Chem Lett 16: 4305-10 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.064
BindingDB Entry DOI: 10.7270/Q28C9VVV
More data for this
Ligand-Target Pair