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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50188814   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50188814
PNG
(8-[2-(4-fluoro-phenyl)-cyclohexyl]-4-phenyl-2,8-di...)
Show SMILES Fc1ccc(cc1)C1CCCCC1N1CCC2(CC1)C(CNC2=O)c1ccccc1
Show InChI InChI=1/C26H31FN2O/c27-21-12-10-19(11-13-21)22-8-4-5-9-24(22)29-16-14-26(15-17-29)23(18-28-25(26)30)20-6-2-1-3-7-20/h1-3,6-7,10-13,22-24H,4-5,8-9,14-18H2,(H,28,30)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 167n/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake at GlyT1


Bioorg Med Chem Lett 16: 4305-10 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.064
BindingDB Entry DOI: 10.7270/Q28C9VVV
More data for this
Ligand-Target Pair