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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50188851   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50188851
PNG
(CHEMBL211525 | rac-4-(4-fluoro-phenyl)-8-(1-isopro...)
Show SMILES CC(C)C1(CCCCC1)N1CCC2(CC1)C(CNC2=O)c1ccc(F)cc1
Show InChI InChI=1S/C23H33FN2O/c1-17(2)23(10-4-3-5-11-23)26-14-12-22(13-15-26)20(16-25-21(22)27)18-6-8-19(24)9-7-18/h6-9,17,20H,3-5,10-16H2,1-2H3,(H,25,27)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 787n/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake at GlyT1


Bioorg Med Chem Lett 16: 4321-5 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.063
BindingDB Entry DOI: 10.7270/Q2P26ZXG
More data for this
Ligand-Target Pair