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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50188883   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50188883
PNG
(CHEMBL378285 | rac-8-(1-phenyl-cyclohexyl)-4-p-tol...)
Show SMILES Cc1ccc(cc1)C1CNC(=O)C11CCN(CC1)C1(CCCCC1)c1ccccc1
Show InChI InChI=1S/C27H34N2O/c1-21-10-12-22(13-11-21)24-20-28-25(30)26(24)16-18-29(19-17-26)27(14-6-3-7-15-27)23-8-4-2-5-9-23/h2,4-5,8-13,24H,3,6-7,14-20H2,1H3,(H,28,30)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 139n/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake at GlyT1


Bioorg Med Chem Lett 16: 4321-5 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.063
BindingDB Entry DOI: 10.7270/Q2P26ZXG
More data for this
Ligand-Target Pair