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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SRC' and Monomerid = 50193873   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50193873
PNG
(7-(2,6-dimethylphenyl)-N-(3,4-dimethylphenyl)-5-me...)
Show SMILES Cc1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)cc1C
Show InChI InChI=1S/C24H24N4/c1-14-9-10-20(12-17(14)4)25-24-26-23-18(5)11-19(13-21(23)27-28-24)22-15(2)7-6-8-16(22)3/h6-13H,1-5H3,(H,25,26,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 957n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50193873
PNG
(7-(2,6-dimethylphenyl)-N-(3,4-dimethylphenyl)-5-me...)
Show SMILES Cc1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)cc1C
Show InChI InChI=1S/C24H24N4/c1-14-9-10-20(12-17(14)4)25-24-26-23-18(5)11-19(13-21(23)27-28-24)22-15(2)7-6-8-16(22)3/h6-13H,1-5H3,(H,25,26,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 960n/an/an/an/an/an/a



TargeGen, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Src kinase


Bioorg Med Chem Lett 16: 5546-50 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.035
BindingDB Entry DOI: 10.7270/Q2SN08MP
More data for this
Ligand-Target Pair