BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SRC' and Monomerid = 50193882   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50193882
PNG
(CHEMBL220912 | N1-(7-(2,6-dimethylphenyl)-5-methyl...)
Show SMILES CN(C)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)cc1
Show InChI InChI=1S/C24H25N5/c1-15-7-6-8-16(2)22(15)18-13-17(3)23-21(14-18)27-28-24(26-23)25-19-9-11-20(12-10-19)29(4)5/h6-14H,1-5H3,(H,25,26,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 240n/an/an/an/an/an/a



TargeGen, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Src kinase


Bioorg Med Chem Lett 16: 5546-50 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.035
BindingDB Entry DOI: 10.7270/Q2SN08MP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50193882
PNG
(CHEMBL220912 | N1-(7-(2,6-dimethylphenyl)-5-methyl...)
Show SMILES CN(C)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)cc1
Show InChI InChI=1S/C24H25N5/c1-15-7-6-8-16(2)22(15)18-13-17(3)23-21(14-18)27-28-24(26-23)25-19-9-11-20(12-10-19)29(4)5/h6-14H,1-5H3,(H,25,26,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 244n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair