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Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50196492   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50196492
PNG
(2,9-bis-[2-(2-hydroxy-ethylamino)-ethyl]-anthra[2,...)
Show SMILES OCCNCCn1c(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)c1=O)c46)c(=O)n(CCNCCO)c5=O
Show InChI InChI=1S/C32H28N4O6/c37-15-11-33-9-13-35-29(39)21-5-1-17-18-2-6-23-28-24(32(42)36(31(23)41)14-10-34-12-16-38)8-4-20(26(18)28)19-3-7-22(30(35)40)27(21)25(17)19/h1-8,33-34,37-38H,9-16H2
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Similars

Article
PubMed
n/an/a 60n/an/an/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Inhibition of telomerase in JR8 cell extract by TRAP assay


Bioorg Med Chem 15: 555-62 (2006)


Article DOI: 10.1016/j.bmc.2006.09.029
BindingDB Entry DOI: 10.7270/Q2QC033H
More data for this
Ligand-Target Pair