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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SRC' and Monomerid = 50198379   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50198379
PNG
(CHEMBL227836 | N-(2,6-dimethylphenyl)-5-[4-(2-morp...)
Show SMILES Cc1cccc(C)c1Nc1ncc(-c2ccc(OCCN3CCOCC3)cc2)n2cncc12
Show InChI InChI=1S/C26H29N5O2/c1-19-4-3-5-20(2)25(19)29-26-24-16-27-18-31(24)23(17-28-26)21-6-8-22(9-7-21)33-15-12-30-10-13-32-14-11-30/h3-9,16-18H,10-15H2,1-2H3,(H,28,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 37n/an/an/an/an/an/a



Kissei Pharmaceutical Company Ltd

Curated by ChEMBL


Assay Description
Inhibition of cSrc by coupled spectrophotometric enzyme assay


Bioorg Med Chem 15: 868-85 (2006)


Article DOI: 10.1016/j.bmc.2006.10.041
BindingDB Entry DOI: 10.7270/Q2DZ094H
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50198379
PNG
(CHEMBL227836 | N-(2,6-dimethylphenyl)-5-[4-(2-morp...)
Show SMILES Cc1cccc(C)c1Nc1ncc(-c2ccc(OCCN3CCOCC3)cc2)n2cncc12
Show InChI InChI=1S/C26H29N5O2/c1-19-4-3-5-20(2)25(19)29-26-24-16-27-18-31(24)23(17-28-26)21-6-8-22(9-7-21)33-15-12-30-10-13-32-14-11-30/h3-9,16-18H,10-15H2,1-2H3,(H,28,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 700n/an/an/an/an/an/a



Kissei Pharmaceutical Company Ltd

Curated by ChEMBL


Assay Description
Inhibition of cSrc in COS7 cells by ELISA


Bioorg Med Chem 15: 868-85 (2006)


Article DOI: 10.1016/j.bmc.2006.10.041
BindingDB Entry DOI: 10.7270/Q2DZ094H
More data for this
Ligand-Target Pair